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OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma

BACKGROUND: The successful gene delivery into the brain is a major challenge due to the presence of the blood–brain barrier (BBB). In order to transport plasmid DNA across the BBB and target the brain glioma, the PEGylated liposomes (PLs) modified with OX26 and chlorotoxin (CTX) were developed as a...

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Autors principals: Yue, Pei-jian, He, Lei, Qiu, Shu-wei, Li, Yi, Liao, Yi-ji, Li, Xiang-pen, Xie, Dan, Peng, Ying
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137094/
https://ncbi.nlm.nih.gov/pubmed/25128329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-191
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