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Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience

Convection-enhanced delivery (CED) of highly stable PEGylated liposomes encapsulating chemotherapeutic drugs has previously been effective against malignant glioma xenografts. We have developed a novel, convectable non-PEGylated liposomal formulation that can be used to encapsulate both the topoisom...

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Detalhes bibliográficos
Main Authors: Grahn, Amy Y., Bankiewicz, Krystof S., Dugich-Djordjevic, Millicent, Bringas, John R., Hadaczek, Piotr, Johnson, Greg A., Eastman, Simon, Luz, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759007/
https://ncbi.nlm.nih.gov/pubmed/19466380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-009-9917-1
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