High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor

Guanylyl cyclases (GCs), which synthesize the messenger cyclic guanosine 3′,5′-monophosphate, control several sensory functions, such as phototransduction, chemosensation, and thermosensation, in many species from worms to mammals. The GC chemoreceptor in sea urchin sperm can decode chemoattractant...

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Detalhes bibliográficos
Main Authors: Pichlo, Magdalena, Bungert-Plümke, Stefanie, Weyand, Ingo, Seifert, Reinhard, Bönigk, Wolfgang, Strünker, Timo, Kashikar, Nachiket Dilip, Goodwin, Normann, Müller, Astrid, Körschen, Heinz G., Collienne, Ursel, Pelzer, Patric, Van, Qui, Enderlein, Jörg, Klemm, Clementine, Krause, Eberhard, Trötschel, Christian, Poetsch, Ansgar, Kremmer, Elisabeth, Kaupp, U. Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137060/
https://ncbi.nlm.nih.gov/pubmed/25135936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201402027
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