High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor

Guanylyl cyclases (GCs), which synthesize the messenger cyclic guanosine 3′,5′-monophosphate, control several sensory functions, such as phototransduction, chemosensation, and thermosensation, in many species from worms to mammals. The GC chemoreceptor in sea urchin sperm can decode chemoattractant...

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Autors principals: Pichlo, Magdalena, Bungert-Plümke, Stefanie, Weyand, Ingo, Seifert, Reinhard, Bönigk, Wolfgang, Strünker, Timo, Kashikar, Nachiket Dilip, Goodwin, Normann, Müller, Astrid, Körschen, Heinz G., Collienne, Ursel, Pelzer, Patric, Van, Qui, Enderlein, Jörg, Klemm, Clementine, Krause, Eberhard, Trötschel, Christian, Poetsch, Ansgar, Kremmer, Elisabeth, Kaupp, U. Benjamin
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
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Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137060/
https://ncbi.nlm.nih.gov/pubmed/25135936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201402027
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