The solute carrier SLC9C1 is a Na(+)/H(+)-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding

Voltage-sensing (VSD) and cyclic nucleotide-binding domains (CNBD) gate ion channels for rapid electrical signaling. By contrast, solute carriers (SLCs) that passively redistribute substrates are gated by their substrates themselves. Here, we study the orphan sperm-specific solute carriers SLC9C1 th...

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Publicado en:Nat Commun
Main Authors: Windler, F., Bönigk, W., Körschen, H. G., Grahn, E., Strünker, T., Seifert, R., Kaupp, U. B.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052114/
https://ncbi.nlm.nih.gov/pubmed/30022052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05253-x
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