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Loss of Fbw7 Reprograms Adult Pancreatic Ductal Cells into α, δ, and β Cells
The adult pancreas is capable of limited regeneration after injury but has no defined stem cell population. The cell types and molecular signals that govern the production of new pancreatic tissue are not well understood. Here, we show that inactivation of the SCF-type E3 ubiquitin ligase substrate...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136739/ https://ncbi.nlm.nih.gov/pubmed/25105579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.06.019 |
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