Modification and Biological Evaluation of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion

[Image: see text] Fascin has recently emerged as a potential therapeutic target, as its expression in cancer cells is closely associated with tumor progression and metastasis. Following the initial discovery of a series of thiazole derivatives that demonstrated potent antimigration and antiinvasion...

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Библиографические подробности
Главные авторы: Zheng, Shilong, Zhong, Qiu, Xi, Yulan, Mottamal, Madhusoodanan, Zhang, Qiang, Schroeder, Richard L., Sridhar, Jayalakshmi, He, Ling, McFerrin, Harris, Wang, Guangdi
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136724/
https://ncbi.nlm.nih.gov/pubmed/25007006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500724x
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