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From Pure Antagonists to Pure Degraders of the Estrogen Receptor: Evolving Strategies for the Same Target
[Image: see text] Pure antiestrogens, or selective estrogen receptor degraders (SERDs), have proven to be effective in treating breast cancer that has progressed on tamoxifen and/or aromatase inhibitors. However, the only FDA-approved pure antiestrogen, fulvestrant, is limited in efficacy by its low...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2021
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8047716/ https://ncbi.nlm.nih.gov/pubmed/33869913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c06362 |
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