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Therapeutic Potential of Targeting the Oncogenic SHP2 Phosphatase

[Image: see text] The Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic phosphatase associated with various kinds of leukemia and solid tumors. Thus, there is substantial interest in developing SHP2 inhibitors as potential anticancer and antileukemia agents. Usin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zeng, Li-Fan, Zhang, Ruo-Yu, Yu, Zhi-Hong, Li, Sijiu, Wu, Li, Gunawan, Andrea M., Lane, Brandon S., Mali, Raghuveer S., Li, Xingjun, Chan, Rebecca J., Kapur, Reuben, Wells, Clark D., Zhang, Zhong-Yin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Chemical Society 2014
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136714/
https://ncbi.nlm.nih.gov/pubmed/25003231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5006176
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