A carregar...
Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening
SHP2, encoded by PTPN11, is a non-receptor protein tyrosine phosphatase (PTP) containing two tandem Src homology-2 (SH2) domains. It is expressed ubiquitously and plays critical roles in growth factor mediated processes, primarily by promoting the activation of the RAS/ERK signaling pathway. Genetic...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128679/ https://ncbi.nlm.nih.gov/pubmed/21669525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.078 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|