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Chronic exposure to the cytolethal distending toxins of Gram-negative bacteria promotes genomic instability and altered DNA damage response

Epidemiological evidence links chronic bacterial infections to the increased incidence of certain types of cancer but the molecular mechanisms by which bacteria contribute to tumour initiation and progression are still poorly characterized. Here we show that chronic exposure to the genotoxin cytolet...

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Bibliographic Details
Main Authors: Guidi, Riccardo, Guerra, Lina, Levi, Laura, Stenerlöw, Bo, Fox, James G., Josenhans, Christine, Masucci, Maria G., Frisan, Teresa
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136655/
https://ncbi.nlm.nih.gov/pubmed/22998585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12034
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