Cytolethal Distending Toxin Damages the Oral Epithelium of Gingival Explants

The cytolethal distending toxin (Cdt), expressed by the periodontal pathogen Aggregatibacter actinomycetemcomitans, inhibits the proliferation of cultured epithelial cells by arresting the cell cycle. The gingival epithelium is an early line of defense against microbial assault. When damaged, bacter...

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Bibliographic Details
Main Authors: Damek-Poprawa, M., Haris, M., Volgina, A., Korostoff, J., DiRienzo, J.M.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2011
Subjects:
Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148007/
https://ncbi.nlm.nih.gov/pubmed/21471326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034511403743
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