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Cytolethal Distending Toxin Damages the Oral Epithelium of Gingival Explants

The cytolethal distending toxin (Cdt), expressed by the periodontal pathogen Aggregatibacter actinomycetemcomitans, inhibits the proliferation of cultured epithelial cells by arresting the cell cycle. The gingival epithelium is an early line of defense against microbial assault. When damaged, bacter...

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Main Authors: Damek-Poprawa, M., Haris, M., Volgina, A., Korostoff, J., DiRienzo, J.M.
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148007/
https://ncbi.nlm.nih.gov/pubmed/21471326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034511403743
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