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Chronic exposure to the cytolethal distending toxins of Gram-negative bacteria promotes genomic instability and altered DNA damage response

Epidemiological evidence links chronic bacterial infections to the increased incidence of certain types of cancer but the molecular mechanisms by which bacteria contribute to tumour initiation and progression are still poorly characterized. Here we show that chronic exposure to the genotoxin cytolet...

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Detalhes bibliográficos
Main Authors: Guidi, Riccardo, Guerra, Lina, Levi, Laura, Stenerlöw, Bo, Fox, James G., Josenhans, Christine, Masucci, Maria G., Frisan, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136655/
https://ncbi.nlm.nih.gov/pubmed/22998585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12034
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