Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy

We report the solution structure of Escherichia coli β-galactosidase (∼465 kDa), solved at ∼3.2-Å resolution by using single-particle cryo-electron microscopy (cryo-EM). Densities for most side chains, including those of residues in the active site, and a catalytic Mg(2+) ion can be discerned in the...

Full description

Saved in:
Bibliographic Details
Main Authors: Bartesaghi, Alberto, Matthies, Doreen, Banerjee, Soojay, Merk, Alan, Subramaniam, Sriram
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136629/
https://ncbi.nlm.nih.gov/pubmed/25071206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402809111
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items