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Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
The liver is a key metabolic organ that controls whole-body physiology in response to nutrient availability. Mammalian target of rapamycin (mTOR) is a nutrient-activated kinase and central controller of growth and metabolism that is negatively regulated by the tumor suppressor tuberous sclerosis com...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136616/ https://ncbi.nlm.nih.gov/pubmed/25082895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412047111 |
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