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Targeting the B cell receptor signaling pathway in B lymphoid malignancies
PURPOSE OF REVIEW: Normal B cells that failed to productively rearrange immunoglobulin V region genes, encoding a functional B cell receptor (BCR) are destined to die. Likewise, the majority of B cell malignancies remain dependent on functional BCR signaling, while in some subtypes BCR expression is...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136419/ https://ncbi.nlm.nih.gov/pubmed/24811161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000048 |
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