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Targeting the B cell receptor signaling pathway in B lymphoid malignancies

PURPOSE OF REVIEW: Normal B cells that failed to productively rearrange immunoglobulin V region genes, encoding a functional B cell receptor (BCR) are destined to die. Likewise, the majority of B cell malignancies remain dependent on functional BCR signaling, while in some subtypes BCR expression is...

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Détails bibliographiques
Auteurs principaux: Buchner, Maike, Müschen, Markus
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136419/
https://ncbi.nlm.nih.gov/pubmed/24811161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000048
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