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The B-cell receptor signaling pathway as a therapeutic target in CLL

Targeted therapy with imatinib and other selective tyrosine kinase inhibitors has transformed the treatment of chronic myeloid leukemia. Unlike chronic myeloid leukemia, chronic lymphocytic leukemia (CLL) lacks a common genetic aberration amenable to therapeutic targeting. However, our understanding...

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Detalhes bibliográficos
Main Authors: Woyach, Jennifer A., Johnson, Amy J., Byrd, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418714/
https://ncbi.nlm.nih.gov/pubmed/22715122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-362624
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