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The B-cell receptor signaling pathway as a therapeutic target in CLL

Targeted therapy with imatinib and other selective tyrosine kinase inhibitors has transformed the treatment of chronic myeloid leukemia. Unlike chronic myeloid leukemia, chronic lymphocytic leukemia (CLL) lacks a common genetic aberration amenable to therapeutic targeting. However, our understanding...

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Hlavní autoři: Woyach, Jennifer A., Johnson, Amy J., Byrd, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418714/
https://ncbi.nlm.nih.gov/pubmed/22715122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-362624
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