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The B-cell receptor signaling pathway as a therapeutic target in CLL

Targeted therapy with imatinib and other selective tyrosine kinase inhibitors has transformed the treatment of chronic myeloid leukemia. Unlike chronic myeloid leukemia, chronic lymphocytic leukemia (CLL) lacks a common genetic aberration amenable to therapeutic targeting. However, our understanding...

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Détails bibliographiques
Auteurs principaux: Woyach, Jennifer A., Johnson, Amy J., Byrd, John C.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418714/
https://ncbi.nlm.nih.gov/pubmed/22715122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-362624
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