Preformulation studies of EFdA, a novel nucleoside reverse transcriptase inhibitor for HIV prevention

4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) is a novel nucleoside analog of great interest because of its superior activity against wild-type and multidrug-resistant HIV-1 strains, and favorable safety profiles in vitro and in vivo. The aim of this work was to provide preformulation information of...

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Hlavní autoři: Zhang, Wei, Parniak, Michael A., Mitsuya, Hiroaki, Sarafianos, Stefan G., Graebing, Phillip W., Rohan, Lisa C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136418/
https://ncbi.nlm.nih.gov/pubmed/23841536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03639045.2013.809535
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