Impact of Distinct Poxvirus Infections on the Specificities and Functionalities of CD4(+) T Cell Responses

The factors that determine CD4(+) T cell (T(CD4(+))) specificities, functional capacity, and memory persistence in response to complex pathogens remain unclear. We explored these parameters in the C57BL/6 mouse through comparison of two highly related (>92% homology) poxviruses: ectromelia virus...

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Detalhes bibliográficos
Main Authors: Siciliano, Nicholas A., Hersperger, Adam R., Lacuanan, Aimee M., Xu, Ren-Huan, Sidney, John, Sette, Alessandro, Sigal, Luis J., Eisenlohr, Laurence C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136331/
https://ncbi.nlm.nih.gov/pubmed/24965457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01150-14
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