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Perforin-dependent CD4(+) T-cell cytotoxicity contributes to control a murine poxvirus infection
CD4(+) T cells are generally regarded as helpers and regulators of the immune response. Although cytolytic CD4(+) T cells have been described, whether those generated during the course of a viral infection play a role in virus control remains unknown. Here we show that during acute infection with ec...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382508/ https://ncbi.nlm.nih.gov/pubmed/22665800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202143109 |
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