Restriction of HIV-1 by Rhesus TRIM5α Is Governed by Alpha Helices in the Linker2 Region

TRIM5α proteins are a potent barrier to the cross-species transmission of retroviruses. TRIM5α proteins exhibit an ability to self-associate at many levels, ultimately leading to the formation of protein assemblies with hexagonal symmetry in vitro and cytoplasmic assemblies when expressed in cells....

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Autors principals: Sastri, Jaya, Johnsen, Laura, Smolin, Nikolai, Imam, Sabrina, Mukherjee, Santanu, Lukic, Zana, Brandariz-Nuñez, Alberto, Robia, Seth L., Diaz-Griffero, Felipe, Wiethoff, Christopher, Campbell, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136267/
https://ncbi.nlm.nih.gov/pubmed/24872590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01134-14
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