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Transfer of the Amino-Terminal Nuclear Envelope Targeting Domain of Human MX2 Converts MX1 into an HIV-1 Resistance Factor

The myxovirus resistance 2 (MX2) protein of humans has been identified recently as an interferon (IFN)-inducible inhibitor of human immunodeficiency virus type 1 (HIV-1) that acts at a late postentry step of infection to prevent the nuclear accumulation of viral cDNA (C. Goujon et al., Nature 502:55...

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Detalhes bibliográficos
Main Authors: Goujon, Caroline, Moncorgé, Olivier, Bauby, Hélène, Doyle, Tomas, Barclay, Wendy S., Malim, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136259/
https://ncbi.nlm.nih.gov/pubmed/24899177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01269-14
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