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Target Cell-Mediated Editing of HIV-1 cDNA by APOBEC3 Proteins in Human Macrophages
Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) proteins are encapsidated by assembling HIV-1 virions and edit viral cDNA in the next round of infection. Using alpha interferon (IFN-α)-treated monocyte-derived macrophages, we show that infrequent editing of HIV-1 reverse...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233168/ https://ncbi.nlm.nih.gov/pubmed/21957290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00775-11 |
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