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Human APOBEC3G-Mediated Editing Can Promote HIV-1 Sequence Diversification and Accelerate Adaptation to Selective Pressure

Human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G, hereinafter referred to as A3G) is an innate virus restriction factor that inhibits human immunodeficiency virus type 1 (HIV-1) replication and induces excessive deamination of cytidine residues in nascent reverse tr...

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Detalhes bibliográficos
Main Authors: Kim, Eun-Young, Bhattacharya, Tanmoy, Kunstman, Kevin, Swantek, Peter, Koning, Fransje A., Malim, Michael H., Wolinsky, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937764/
https://ncbi.nlm.nih.gov/pubmed/20660203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01223-10
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