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Hypermutation of an Ancient Human Retrovirus by APOBEC3G

Human endogenous retroviruses (HERVs) comprise approximately 8% of the human genome, but all are remnants of ancient retroviral infections and harbor inactivating mutations that render them replication defective. Nevertheless, as viral “fossils,” HERVs may provide insights into ancient retrovirus-ho...

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Detalhes bibliográficos
Main Authors: Lee, Young Nam, Malim, Michael H., Bieniasz, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519637/
https://ncbi.nlm.nih.gov/pubmed/18562521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00751-08
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