Conserved Footprints of APOBEC3G on Hypermutated Human Immunodeficiency Virus Type 1 and Human Endogenous Retrovirus HERV-K(HML2) Sequences

The human polynucleotide cytidine deaminases APOBEC3G (hA3G) and APOBEC3F (hA3F) are antiviral restriction factors capable of inducing extensive plus-strand guanine-to-adenine (G-to-A) hypermutation in a variety of retroviruses and retroelements, including human immunodeficiency virus type 1 (HIV-1)...

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Detalhes bibliográficos
Main Authors: Armitage, Andrew E., Katzourakis, Aris, de Oliveira, Tulio, Welch, John J., Belshaw, Robert, Bishop, Kate N., Kramer, Beatrice, McMichael, Andrew J., Rambaut, Andrew, Iversen, Astrid K. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519685/
https://ncbi.nlm.nih.gov/pubmed/18562517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00584-08
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