Selective Pharmacologic Inhibition of a PASTA Kinase Increases Listeria monocytogenes Susceptibility to β-Lactam Antibiotics

While β-lactam antibiotics are a critical part of the antimicrobial arsenal, they are frequently compromised by various resistance mechanisms, including changes in penicillin binding proteins of the bacterial cell wall. Genetic deletion of the penicillin binding protein and serine/threonine kinase-a...

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Autors principals: Pensinger, Daniel A., Aliota, Matthew T., Schaenzer, Adam J., Boldon, Kyle M., Ansari, Israr-ul H., Vincent, William J. B., Knight, Benjamin, Reniere, Michelle L., Striker, Rob, Sauer, John-Demian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135996/
https://ncbi.nlm.nih.gov/pubmed/24867981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02396-14
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