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Selective Pharmacologic Inhibition of a PASTA Kinase Increases Listeria monocytogenes Susceptibility to β-Lactam Antibiotics

While β-lactam antibiotics are a critical part of the antimicrobial arsenal, they are frequently compromised by various resistance mechanisms, including changes in penicillin binding proteins of the bacterial cell wall. Genetic deletion of the penicillin binding protein and serine/threonine kinase-a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pensinger, Daniel A., Aliota, Matthew T., Schaenzer, Adam J., Boldon, Kyle M., Ansari, Israr-ul H., Vincent, William J. B., Knight, Benjamin, Reniere, Michelle L., Striker, Rob, Sauer, John-Demian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135996/
https://ncbi.nlm.nih.gov/pubmed/24867981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02396-14
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