Selective Pharmacologic Inhibition of a PASTA Kinase Increases Listeria monocytogenes Susceptibility to β-Lactam Antibiotics

While β-lactam antibiotics are a critical part of the antimicrobial arsenal, they are frequently compromised by various resistance mechanisms, including changes in penicillin binding proteins of the bacterial cell wall. Genetic deletion of the penicillin binding protein and serine/threonine kinase-a...

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Main Authors: Pensinger, Daniel A., Aliota, Matthew T., Schaenzer, Adam J., Boldon, Kyle M., Ansari, Israr-ul H., Vincent, William J. B., Knight, Benjamin, Reniere, Michelle L., Striker, Rob, Sauer, John-Demian
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135996/
https://ncbi.nlm.nih.gov/pubmed/24867981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02396-14
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