Evaluation of the Pharmacokinetics and Pharmacodynamics of Liposomal Amikacin for Inhalation in Cystic Fibrosis Patients with Chronic Pseudomonal Infections Using Data from Two Phase 2 Clinical Studies

The pharmacokinetic-pharmacodynamic (PK-PD) relationships between serum exposure measures of liposomal amikacin for inhalation (LAI) and the change in pulmonary function test (PFT) measures and number of CFU from baseline were evaluated in cystic fibrosis (CF) patients chronically infected with Pseu...

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Main Authors: Okusanya, Olanrewaju O., Bhavnani, Sujata M., Hammel, Jeffrey P., Forrest, Alan, Bulik, Catharine C., Ambrose, Paul G., Gupta, Renu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135881/
https://ncbi.nlm.nih.gov/pubmed/24687506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02421-13
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