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Pharmacokinetic and Pharmacodynamic Evaluation of Liposomal Amikacin for Inhalation in Cystic Fibrosis Patients with Chronic Pseudomonal Infection

The pharmacokinetics and pharmacodynamics of a novel liposomal amikacin for inhalation were evaluated in cystic fibrosis patients with chronic pseudomonas infection. Twenty-four patients from two studies received 500 mg of liposomal amikacin by inhalation once daily for 14 days. Serum, sputum, and 2...

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Main Authors: Okusanya, Ólanrewaju O., Bhavnani, Sujata M., Hammel, Jeffrey, Minic, Predrag, Dupont, Lieven J., Forrest, Alan, Mulder, Geert-Jan, Mackinson, Constance, Ambrose, Paul G., Gupta, Renu
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737891/
https://ncbi.nlm.nih.gov/pubmed/19451281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00872-08
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