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Cell Activation-Induced Phosphoinositide 3-Kinase Alpha/Beta Dimerization Regulates PTEN Activity

The phosphoinositide 3-kinase (PI3K)/PTEN (phosphatase and tensin homolog) pathway is one of the central routes that enhances cell survival, division, and migration, and it is frequently deregulated in cancer. PI3K catalyzes formation of phosphatidylinositol 3,4,5-triphosphate [PI(3,4,5)P(3)] after...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pérez-García, Vicente, Redondo-Muñoz, Javier, Kumar, Amit, Carrera, Ana C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135622/
https://ncbi.nlm.nih.gov/pubmed/24958106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00167-14
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