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Phosphoinositide 3-Kinase Beta Protects Nuclear Envelope Integrity by Controlling RCC1 Localization and Ran Activity

The nuclear envelope (NE) forms a barrier between the nucleus and the cytosol that preserves genomic integrity. The nuclear lamina and nuclear pore complexes (NPCs) are NE components that regulate nuclear events through interaction with other proteins and DNA. Defects in the nuclear lamina are assoc...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Redondo-Muñoz, Javier, Pérez-García, Vicente, Rodríguez, María J., Valpuesta, José M., Carrera, Ana C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295382/
https://ncbi.nlm.nih.gov/pubmed/25348717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01184-14
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