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Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis
Class I(A) phosphoinositide 3-kinases (PI3K) are enzymes composed of a p85 regulatory and a p110 catalytic subunit that control formation of 3-poly-phosphoinositides (PIP(3)). The PI3K pathway regulates cell survival, migration, and division, and is mutated in approximately half of human tumors. For...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Cell Biology
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510015/ https://ncbi.nlm.nih.gov/pubmed/23051731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0371 |
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