p85β phosphoinositide 3-kinase subunit regulates tumor progression

PIK3R2 encodes a ubiquitous regulatory subunit (p85β) of PI3K, an enzyme that generates 3-polyphosphoinositides at the plasma membrane. PI3K activation triggers cell survival and migration. We found that p85β expression is elevated in breast and colon carcinomas and that its increased expression cor...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cortés, Isabel, Sánchez-Ruíz, Jesús, Zuluaga, Susana, Calvanese, Vincenzo, Marqués, Miriam, Hernández, Carmen, Rivera, Teresa, Kremer, Leonor, González-García, Ana, Carrera, Ana C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396516/
https://ncbi.nlm.nih.gov/pubmed/22733740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118138109
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