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p85β phosphoinositide 3-kinase subunit regulates tumor progression
PIK3R2 encodes a ubiquitous regulatory subunit (p85β) of PI3K, an enzyme that generates 3-polyphosphoinositides at the plasma membrane. PI3K activation triggers cell survival and migration. We found that p85β expression is elevated in breast and colon carcinomas and that its increased expression cor...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396516/ https://ncbi.nlm.nih.gov/pubmed/22733740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118138109 |
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