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Specific function of phosphoinositide 3-kinase beta in the control of DNA replication

Class I(A) phosphoinositide 3-kinase (PI3K) are enzymes comprised of a p85 regulatory and a p110 catalytic subunit that induce formation of 3-polyphosphoinositides, which activate numerous downstream targets. PI3K controls cell division. Of the 2 ubiquitous PI3K isoforms, α has selective action in c...

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Bibliografische gegevens
Hoofdauteurs: Marqués, Miriam, Kumar, Amit, Poveda, Ana M., Zuluaga, Susana, Hernández, Carmen, Jackson, Shaun, Pasero, Philippe, Carrera, Ana C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678616/
https://ncbi.nlm.nih.gov/pubmed/19416922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812000106
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