Cell Activation-Induced Phosphoinositide 3-Kinase Alpha/Beta Dimerization Regulates PTEN Activity

The phosphoinositide 3-kinase (PI3K)/PTEN (phosphatase and tensin homolog) pathway is one of the central routes that enhances cell survival, division, and migration, and it is frequently deregulated in cancer. PI3K catalyzes formation of phosphatidylinositol 3,4,5-triphosphate [PI(3,4,5)P(3)] after...

Full description

Saved in:
Bibliographic Details
Main Authors: Pérez-García, Vicente, Redondo-Muñoz, Javier, Kumar, Amit, Carrera, Ana C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135622/
https://ncbi.nlm.nih.gov/pubmed/24958106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00167-14
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items