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Regulated Proteolysis of NOTCH2 and NOTCH3 Receptors by ADAM10 and Presenilins
In mammals, there are four NOTCH receptors and five Delta-Jagged-type ligands regulating many aspects of embryonic development and adult tissue homeostasis. NOTCH proteins are type I transmembrane receptors that interact with ligands on adjacent cells and are activated by regulated intramembrane pro...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135574/ https://ncbi.nlm.nih.gov/pubmed/24842903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00206-14 |
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