A 1536-well Fluorescence Polarization Assay to Screen for Modulators of the MUSASHI Family of RNA-Binding Proteins

RNA-binding proteins (RBPs) can act as stem cell modulators and oncogenic drivers, but have been largely ignored by the pharmaceutical industry as potential therapeutic targets for cancer. The MUSASHI (MSI) family has recently been demonstrated to be an attractive clinical target in the most aggress...

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Bibliographic Details
Main Authors: Minuesa, Gerard, Antczak, Christophe, Shum, David, Radu, Constantin, Bhinder, Bhavneet, Li, Yueming, Djaballah, Hakim, Kharas, Michael G.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135234/
https://ncbi.nlm.nih.gov/pubmed/24912481
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