A Miniaturized 1536-Well Format γ-Secretase Assay

γ-Secretase is an aspartyl protease that cleaves multiple substrates including the amyloid precursor protein (APP) and the Notch proteins. Abnormal proteolysis of APP is involved in the pathogenesis of Alzheimer’s disease (AD) and overactive Notch signaling plays an oncogenic role in a variety of ca...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Shelton, Christopher C., Tian, Yuan, Shum, David, Radu, Constantin, Djaballah, Hakim, Li, Yue-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. publishers 2009
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096545/
https://ncbi.nlm.nih.gov/pubmed/19715456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2009.0202
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares