The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

The t(8;21) translocation is one of the most frequent chromosome abnormalities in acute myeloid leukemia. It has been shown that the t(8;21) breakpoints on chromosome 21 cluster within a single specific intron of the AML1 gene, which is highly homologous to the Drosophila segmentation gene runt. Her...

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Pubblicato in:	EMBO J
Autori principali:	Miyoshi, H, Kozu, T, Shimizu, K, Enomoto, K, Maseki, N, Kaneko, Y, Kamada, N, Ohki, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8334990/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05933.x
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