The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

The t(8;21) translocation is one of the most frequent chromosome abnormalities in acute myeloid leukemia. It has been shown that the t(8;21) breakpoints on chromosome 21 cluster within a single specific intron of the AML1 gene, which is highly homologous to the Drosophila segmentation gene runt. Her...

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Hlavní autoři: Miyoshi, H, Kozu, T, Shimizu, K, Enomoto, K, Maseki, N, Kaneko, Y, Kamada, N, Ohki, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC413521/
https://ncbi.nlm.nih.gov/pubmed/8334990
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