The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

Benzer Materyaller

• t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.
  Yazar:: Miyoshi, H, ve diğerleri
  Baskı/Yayın Bilgisi: (1991)
• The AML1-MTG8 Leukemic Fusion Protein Forms a Complex with a Novel Member of the MTG8(ETO/CDR) Family, MTGR1
  Yazar:: Kitabayashi, Issay, ve diğerleri
  Baskı/Yayın Bilgisi: (1998)
• The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation.
  Yazar:: Meyers, S, ve diğerleri
  Baskı/Yayın Bilgisi: (1995)
• siRNAs targeting the ERK2 signaling pathway and AML1/MTG8 fusion gene attenuate the differentiation, proliferation and growth arrest in t(8;21) leukemia
  Yazar:: Bashanfer, Salem, ve diğerleri
  Baskı/Yayın Bilgisi: (2012)
• Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide.
  Yazar:: Sakakura, C, ve diğerleri
  Baskı/Yayın Bilgisi: (1994)