Anti-VEGF antibodies mitigate the development of radiation necrosis in mouse brain

PURPOSE: To quantify the effectiveness of anti-VEGF antibodies (bevacizumab and B20-4.1.1) as mitigators of radiation-induced, CNS (brain) necrosis in a mouse model. EXPERIMENTAL DESIGN: Cohorts of mice were irradiated with single-fraction 50- or 60-Gy doses of radiation targeted to the left hemisph...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jiang, Xiaoyu, Engelbach, John A, Yuan, Liya, Cates, Jeremy, Gao, Feng, Drzymala, Robert E, Hallahan, Dennis E, Rich, Keith M, Schmidt, Robert E, Ackerman, Joseph JH, Garbow, Joel R
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135174/
https://ncbi.nlm.nih.gov/pubmed/24647570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1941
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados