A Gamma-Knife-Enabled Mouse Model of Cerebral Single-Hemisphere Delayed Radiation Necrosis

PURPOSE: To develop a Gamma Knife-based mouse model of late time-to-onset, cerebral radiation necrosis (RN) with serial evaluation by magnetic resonance imaging (MRI) and histology. METHODS AND MATERIALS: Mice were irradiated with the Leksell Gamma Knife(®) (GK) Perfexion(TM) (Elekta AB; Stockholm,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jiang, Xiaoyu, Yuan, Liya, Engelbach, John A., Cates, Jeremy, Perez-Torres, Carlos J., Gao, Feng, Thotala, Dinesh, Drzymala, Robert E., Schmidt, Robert E., Rich, Keith M., Hallahan, Dennis E., Ackerman, Joseph J. H., Garbow, Joel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595209/
https://ncbi.nlm.nih.gov/pubmed/26440791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139596
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