Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.

In this study we used a dominant-negative FGF receptor mutant to block FGF function in a specific tissue of transgenic mice. The mutant receptor, which is known to block signal transduction in cells when co-expressed with wild-type receptors, was targeted to suprabasal keratinocytes using a keratin...

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Detalhes bibliográficos
Main Authors: Werner, S, Weinberg, W, Liao, X, Peters, K G, Blessing, M, Yuspa, S H, Weiner, R L, Williams, L T
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413510/
https://ncbi.nlm.nih.gov/pubmed/7687538
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