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Interleukin-2 Protects Lupus-prone Mice from Multiple End-organ Damage by Limiting CD4(−)CD8(−) Interleukin-17-producing T-cells
Interleukin-2 (IL-2), a cytokine with pleiotropic effects, is critical for immune cell activation and peripheral tolerance. Although the therapeutic potential of IL-2 has been previously suggested in autoimmune diseases, the mechanisms whereby IL-2 mitigates autoimmunity and prevents organ damage re...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135016/ https://ncbi.nlm.nih.gov/pubmed/25063876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400977 |
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