Compensatory Mechanisms Allow Undersized Anchor-deficient Class I MHC Ligands to Mediate Pathogenic Autoreactive T Cell Responses()

Self-reactive T cells must escape thymic negative selection to mediate pathogenic autoimmunity. In the NOD mouse model of autoimmune diabetes, several β cell-cytotoxic CD8 T cell populations are known, with the most aggressive of these represented by AI4, a T cell clone with promiscuous antigen reco...

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Bibliografiska uppgifter
Huvudupphovsmän: Lamont, Deanna, Mukherjee, Gayatri, Kumar, P. Rajesh, Samanta, Dibyendu, McPhee, Caroline G., Kay, Thomas W. H., Almo, Steven C., DiLorenzo, Teresa P., Serreze, David V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134999/
https://ncbi.nlm.nih.gov/pubmed/25063871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400997
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